How NAD+ IV Therapy May Help Combat Long COVID Fatigue and Brain Fog

Long after recovering from COVID-19, millions of people are still struggling with persistent fatigue, brain fog, muscle weakness, and shortness of breath — a condition now known as Long COVID or Post-Acute Sequelae of SARS-CoV-2 Infection (PASC).

At Elevate Hydration Wellness Clinic, we’re committed to offering science-backed therapies that support recovery at the cellular level — and one of the most promising tools is NAD+ IV therapy.

Understanding the Root Cause: Cellular Energy Collapse

Research has shown that SARS-CoV-2, the virus behind COVID-19, can disrupt the body’s energy-producing machinery — the mitochondria. These tiny powerhouses rely on a molecule called NAD+ (Nicotinamide Adenine Dinucleotide) to generate cellular energy (ATP) and repair oxidative damage.

When infection or inflammation depletes NAD+ stores, the result can be:

• Persistent fatigue and low stamina

• Poor concentration and “brain fog”

• Muscle weakness and body aches

• Poor recovery after exertion

This pattern mirrors what many patients experience in Long COVID — a kind of “metabolic burnout” at the cellular level.

The Role of NAD+ in Recovery

NAD+ is essential for:

• Mitochondrial energy production — converting food into ATP

• DNA repair — fixing cellular damage from inflammation

• Immune balance — reducing chronic inflammation and autoimmunity

• Neuroprotection — supporting brain and nerve health

By restoring optimal NAD+ levels, patients often report improved energy, mental clarity, and overall vitality.

Scientific Evidence: How NAD+ May Benefit Long COVID

Recent studies have identified a strong connection between NAD+ depletion and COVID-related inflammation:

• 🧬 NAD+ depletion in Long COVID: A review published in Frontiers in Pharmacology found that viral infections like COVID-19 increase the activity of enzymes (PARPs, CD38) that consume NAD+, leading to cellular exhaustion and immune dysfunction.

• ⚗️ Clinical improvements with NAD+ support: A 2023 pilot study combining low-dose naltrexone (LDN) with NAD+ iontophoresis patches demonstrated significant reductions in fatigue and improved quality-of-life scores among post-COVID patients over 12 weeks.

• 🧠 IV NAD+ as a therapeutic rationale: In Cureus (2022), researchers proposed that IV NAD+ administration could be a promising intervention for Long COVID due to its direct restoration of cellular NAD+ without digestive breakdown losses.

While large-scale clinical trials are still ongoing, this growing body of evidence supports NAD+ therapy as a powerful adjunct for cellular recovery.

Why IV or Injectable NAD+ Works Best

Although oral NAD+ precursors such as NMN or NR can offer mild support, absorption through the digestive tract is limited, and conversion to active NAD+ varies greatly between individuals.

By contrast, IV and injectable NAD+ deliver the coenzyme directly into the bloodstream, bypassing the gut and ensuring maximum bioavailability. This allows your cells to immediately access and utilize NAD+ for:

• Restoring mitochondrial function

• Reducing inflammation

• Enhancing brain and nerve repair

• Supporting detoxification and metabolic balance

At Elevate Hydration Wellness Clinic, our NAD+ IV infusions are carefully formulated to deliver sustained cellular energy and post-viral recovery benefits safely and effectively.

Who Can Benefit from NAD+ IV Therapy

You may be a good candidate for NAD+ therapy if you are experiencing:

• Post-COVID fatigue or lingering “crash” after activity

• Persistent brain fog or cognitive decline

• Mood instability, anxiety, or low motivation

• Chronic inflammation, aches, or poor immune recovery

• General fatigue, burnout, or low metabolism

A Natural Path to Renewed Vitality

At Elevate Hydration Wellness Clinic, we specialize in cellular-level wellness — helping patients feel like themselves again through precision therapies such as IV hydration, vitamin infusions, peptide optimization, and NAD+ therapy.

Our team tailors every protocol to your unique needs, so you can recover faster and elevate your energy naturally.

📍 Elevate Hydration Wellness Clinic

📞 254-987-0774

🌐 www.elevatehydration.org